National League for Nursing (NLN PAX) Practice Exam

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What does the release of thromboplastin from ruptured platelets initiate?

Oxygen release

Blood clot formation

The release of thromboplastin from ruptured platelets is a crucial step in the blood coagulation process, specifically initiating blood clot formation. Thromboplastin, also known as tissue factor, acts as a catalyst that triggers the cascade of reactions involved in the clotting process, converting prothrombin into thrombin. This thrombin then plays a key role in transforming fibrinogen into fibrin, which forms a mesh that captures blood cells and effectively creates a clot to stop bleeding.

This process is essential in responding to vascular injury, as it prevents excessive blood loss and helps maintain hemostasis. Understanding the role of thromboplastin in this process highlights the intricate nature of hemostasis, involving various cellular components and biochemical pathways working together to achieve a critical physiological response.

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White blood cell activation

Hemoglobin synthesis

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